Post-Doctoral Researcher, School of Biochemistry and Cell Biology

Post-Doctoral Researcher, School of Biochemistry and Cell Biology

Registration website

Institution:

University College Cork

Vacancy Category:

Research

Salary From:

€39 130.00

Salary To:

€46 442.00

Contract Type:

Temporary

Vacancy closing date:

2 Dec, 2021

Subject / Area:

Biological SciencesHealth and Medical

Position Summary

Applications are invited for a postdoctoral position in the laboratory of Dr Paul Young in the School of Biochemistry and Cell Biology, University College Cork, Ireland.

Project Details

LNX1 and LNX2 proteins are closely related E3 ubiquitin ligases that are expressed in neurons.  We have described anxiety-related behavioural abnormalities in mice lacking LNX1 and/or LNX2.  Taking advantage of our access to LNX1 and LNX2 knockout mice, this project seeks to identify the developmental processes, neural circuit(s) and molecular mechanisms by which loss of LNX function leads to these behavioural alterations.  The project will also identify the molecular interactions that are relevant to LNX protein function in vivo.  Overall, the project will provide novel insights into the molecular mechanisms underlying brain circuits that control behaviours of relevance to anxiety and autism spectrum disorders and potentially support further investigation of LNX proteins as novel drug targets.

Key Reference

• Young PW: LNX1/LNX2 proteins: functions in neuronal signaling and beyond. Neuronal Signaling 2018, 2(2):1-20.  https://doi.org/10.1042/NS20170191

Position

The position will be based in the School of Biochemistry and Cell Biology, UCC, with the possibility of some travel for international collaboration. The position is funded by Science Foundation Ireland.

Post Duration:

2 Years

Salary:

€39,130 - €46,442 p.a. (IUA Salary Scale)

Project Title: 

Investigation of LNX proteins as novel regulators of synaptic function and potential drug targets in neurological disorders.

For an information package including further details of the post see https://ore.ucc.ie/.

Job ID:

050991.

Informal enquiries can be made in confidence to Dr Paul Young, Senior Lecturer, School of Biochemistry and Cell Biology, Tel: + 353 (0) 21 420 5994; Email: [email protected].

Applications must be submitted online via the University College Cork vacancy portal (https://ore.ucc.ie/). Queries relating to the online application process should be referred to [email protected], quoting the job-title and project name.

Candidates should apply, in confidence, before 12 noon (Irish Local Time) on Thursday, 2 December 2021.

No late applications will be accepted.

Please note that an appointment to posts advertised will be dependent on University approval, together with the terms of the employment control framework for the higher education sector.

UCC is committed to creating and fully embracing an inclusive environment where diversity is celebrated.  As a University we strive to create a workplace that reflects the diversity of our student population where people from a wide variety of backgrounds learn from one another, share ideas, and work collaboratively. UCC is committed to being an employer that recognises the value of diversity amongst its staff.  We encourage applicants to consult our policies at https://www.ucc.ie/en/edi/policies/ and initiatives at https://www.ucc.ie/en/edi/implementation/ and we welcome applications from everyone, including those who are underrepresented in the protected characteristics set out in our Equal Opportunities & Diversity Policy.

UNIVERSITY COLLEGE CORK IS AN EQUAL OPPORTUNITIES EMPLOYER