Research Associate / Fellow (Fixed Term) at the University of Nottingham

We require a motivated and dynamic person to drive development and validation of a pre-clinical, stem-cell based intestinal organoid platform for vaccine development pipelines. This post, funded by the EU and the Innovative Medicines Initiative (IMI), Inno4VAC, is available until 31st August 2023 in the first instance, with the potential to extend up to 3 additional years if research milestones and deliverables are successfully demonstrated.

The purpose of this role will be to develop, characterise and validate a 3D intestinal organoid platform that can model bacterial and viral host-pathogen interactions. The post holder will be expected to plan and conduct work using approaches or methodologies and techniques appropriate to the type of research and will be responsible for writing up their work for publication. To identify opportunities and assist in writing bids for research grant applications. Prepare proposals and applications to both external and/or internal bodies for funding, contractual or accreditation purposes. The post holder will work with hIPSCs and primary intestinal tissue biopsy and culture intestinal organoids in a 3D culture system. Host pathogen interactions using live bacteria, bacterial toxins and virus will also make up a significant part of the research duties along with downstream evaluation of cellular physiological and functional phenotyping.

The role holder will be expected to engage with members of the Hannan lab as well as members of the Inno4VAC consortium as appropriate. The post holder will report to Dr Nicholas Hannan who is the lead investigator on the grant and will have the opportunity to use initiative and creativity to identify areas for research, develop research methods and extend their research portfolio.

Applicants should hold a PhD (or near to completion) in stem cell biology/host pathogen interactions and experience in research area .

This role is fixed term until 31st August 2023. Hours of work are full-time (36.25 hours); however, applications are also welcome from candidates wishing to work part-time (minimum 29 hours per week). Please specify in your application if you wish to work part time and the number of preferred hours.

Informal enquiries may be addressed to Dr. Nick Hannan, email [email protected]. Please note that applications sent directly to this email address will not be accepted.

Our University has always been a supportive, inclusive, caring and positive community. We warmly welcome those of different cultures, ethnicities and beliefs – indeed this very diversity is vital to our success, it is fundamental to our values and enriches life on campus. We welcome applications from UK, Europe and from across the globe. For more information on the support we offer our international colleagues, see our Moving to Nottingham pages.

For successful international applicants, we provide financial support for your visa and the immigration health surcharge, plus an interest-free loan to help cover the cost of immigration-related expenses for any dependants accompanying you to the UK. For more information please see the our webpage on Financial support for visas and the immigration health surcharge.

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MED395321Closing DateSunday, 9th January 2022Job TypeResearchDepartmentSchool of Medicine, Academic Unit 2 Translational Medical Sciences, Cancer & Stem CellsSalary£27924 to £31406 per annum, depending on skills and experience (£31406 with relevant PhD).